MyBioSource.com's PDGFB Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The PDGFB Antibody was generated using PDGF-b, PDGF2, PDGFB, Sis, and SSV as the antigen and it reacts with Human, Mouse, and Rat.
Description
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA By similarity.Li Fang, Arterioscler. Thromb. Vasc. Biol., Apr 2004; 24: 787 - 792. EJ Battegay, J. Cell Biol., May 1994; 125: 917. RA Seifert, J. Biol. Chem., Feb 1993; 268: 4473 - 4480. Jason Liu, Am J Physiol Lung Cell Mol Physiol, May 1998; 274: 702